01-06-2015
Closing the 2014 celebrations of the International Year of Crystallography, FCT-NOVA receives next 05 June at 3 pm in the Library of the Faculty of Science and Technology on Caparica’s campus of, Professor Brian Kobilka, which received the Nobel Prize for Chemistry in 2012 for his work in characterizing the structure and function of cell receptors associated with G protein (known as GPCRs, the expression in English G Protein-Coupled Receptors).
G protein coupled receptors (GPCRs) conduct the majority of transmembrane responses to hormones and neurotransmitters, and mediate the senses of sight, smell and taste. He earned his M.D., cum laude, from Yale University School of Medicine and worked in research as a postdoctoral fellow under Robert Lefkowitz at Duke University, where he started work on cloning the β2-adrenergic receptor. Professor Kobilka was a Howard Hughes Medical Institute (HHMI) investigator from 1987-2003 and moved to Stanford in 1989. He is best known for his research on the structure and activity of G protein-coupled receptors (GPCRs); in particular, work from Kobilka's laboratory determined the molecular structure of the β2-adrenergic receptor.
